Standardized Berberine Hydrochloride from Berberis aristata / Coptis chinensis, 97–98% HPLC. Sourced through qualified production partners for dietary supplement manufacturers.
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Per BRB-001 (Verified 2026-09-20):
| Specification Level | Active Marker |
|---|---|
| Berberine HCl Standard (97%) | HPLC |
| Berberine HCl Premium (98%) | HPLC |
| Berberine HCl Pharma (≥ 99%) | HPLC |
Specifications subject to product requirements and destination-market regulations.
| Botanical source | Berberis aristata / Coptis chinensis |
| Part used | Bark / Root |
| Active marker | Berberine Hydrochloride (isoquinoline alkaloid) |
| Form | Yellow crystalline powder |
| CAS No. | 633-65-8 |
| Molecular formula | C20H18ClNO4 |
| Test Item | Specification | Method |
|---|---|---|
| Appearance | Yellow crystalline powder | Visual |
| Identification | Conforms to reference standard | FT-IR / HPLC |
| Berberine HCl Assay | ≥ 97.0% | HPLC |
| Loss on Drying | ≤ 2.0% | USP <731> |
| Residue on Ignition | ≤ 0.2% | USP <281> |
| Heavy Metals (Pb/As/Cd/Hg) | ≤ 3/1/1/0.1 ppm | ICP-MS |
| Total Plate Count | ≤ 1,000 CFU/g | USP <2021> |
| Yeast & Mold | ≤ 100 CFU/g | USP <2021> |
| E. coli / Salmonella | Negative | USP <2022> |
All specifications subject to product specification and destination-market requirements.
The 97%/98%/99% difference reflects Berberine HCl assay purity measured via HPLC. Higher purity is positioned for pharmaceutical and premium applications.
Berberine HCl is the hydrochloride salt form. It is the most common form in dietary supplements due to higher water solubility compared to free base.
Berberine HCl is commonly combined with Milk Thistle, Alpha Lipoic Acid, and other metabolic support ingredients. We recommend consulting with your formulation team.
Berberine HCl is permitted as a food supplement ingredient in the EU under Novel Food Regulation 2015/2283. Specific regulatory status depends on intended application and labeling.
Berberine HCl content is quantified via HPLC per Chinese Pharmacopoeia and industry-standard methods.
Standard MOQ is 25 kg. Smaller quantities (5-10 kg) are available for evaluation.
Yes. Custom specifications (e.g., specific purity level, packaging) can be discussed with our coordination team.
Standard documentation includes COA, MSDS, allergen statement, Non-GMO statement. Additional documentation available upon request from production partners.
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Data marked as "typical" reflects industry standards; specific values vary by supplier and batch. Documentation including COA, MSDS, allergen, and Non-GMO documentation is available upon request from production partners.
About Nourish Ingredients: We are a China-based sourcing partner for botanical extracts and nutraceutical ingredients. We coordinate supply for international brands — from specification matching to delivery. Production partners maintain FSSC 22000, BRCGS, EU Organic, USDA Organic, FAMI-QS certifications. Documentation available upon request.
For ingredient sourcing inquiries: ashely@nourishingr.com
Reviewed by: Nourish Ingredients Editorial Team Version: 2.3 Last updated: 2026-09-20
| Product Name | Berberine HCL (97%~98%) |
|---|---|
| Main Specs | Berberine HCl 97% / 98% / 99% |
Industry-standard testing indicators. Values vary by specification grade.
| Item | Specification | Test Method |
|---|---|---|
| Appearance | Visual | |
| Assay | HPLC | |
| Particle Size | Sieve | |
| Moisture | u2264 5.0% | GB/T |
| Ash | u2264 5.0% | GB/T |
| Heavy Metals (Pb) | u2264 3 ppm | ICP-MS |
| Heavy Metals (As) | u2264 1 ppm | ICP-MS |
| Heavy Metals (Cd) | u2264 1 ppm | ICP-MS |
| Heavy Metals (Hg) | u2264 0.1 ppm | ICP-MS |
| Total Plate Count | u2264 1,000 CFU/g | GB |
| Yeast & Mold | u2264 100 CFU/g | GB |
| E. coli | Negative | GB |
| Industry | Function | Typical Dosage | Application Forms |
|---|---|---|---|
| Food | |||
| Nutraceutical | |||
| Cosmetic | |||
| Animal Feed |
